1P12

CRYSTAL STRUCTURES OF ALPHA-LYTIC PROTEASE COMPLEXES WITH IRREVERSIBLY BOUND PHOSPHONATE ESTERS

Summary for 1P12

Entry DOI	10.2210/pdb1p12/pdb
Related PRD ID	PRD_000387
Descriptor	ALPHA-LYTIC PROTEASE, PHOSPHONATE ESTER INHIBITOR, SULFATE ION, ... (4 entities in total)
Functional Keywords	serine proteinase, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
Biological source	Lysobacter enzymogenes
Total number of polymer chains	2
Total formula weight	20606.84
Authors	Bone, R.,Agard, D.A. (deposition date: 1990-10-26, release date: 1993-01-15, Last modification date: 2023-11-15)
Primary citation	Bone, R.,Sampson, N.S.,Bartlett, P.A.,Agard, D.A. Crystal structures of alpha-lytic protease complexes with irreversibly bound phosphonate esters. Biochemistry, 30:2263-2272, 1991 Cited by PubMed: 1998685 DOI: 10.1021/bi00222a032 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.9 Å)

Structure validation