1OPC

OMPR DNA-BINDING DOMAIN, ESCHERICHIA COLI

Summary for 1OPC

Entry DOI	10.2210/pdb1opc/pdb
Descriptor	OMPR (2 entities in total)
Functional Keywords	transcription regulation, response regulator, winged helix, osmoregulation
Biological source	Escherichia coli
Cellular location	Cytoplasm: P0AA16
Total number of polymer chains	1
Total formula weight	12538.37
Authors	Martinez-Hackert, E.,Stock, A.M. (deposition date: 1996-12-16, release date: 1997-04-01, Last modification date: 2024-02-14)
Primary citation	Martinez-Hackert, E.,Stock, A.M. The DNA-binding domain of OmpR: crystal structures of a winged helix transcription factor. Structure, 5:109-124, 1997 Cited by PubMed Abstract: The differential expression of the ompF and ompC genes is regulated by two proteins that belong to the two component family of signal transduction proteins: the histidine kinase, EnvZ, and the response regulator, OmpR. OmpR belongs to a subfamily of at least 50 response regulators with homologous C-terminal DNA-binding domains of approximately 98 amino acids. Sequence homology with DNA-binding proteins of known structure cannot be detected, and the lack of structural information has prevented understanding of many of this familys functional properties. PubMed: 9016718 DOI: 10.1016/S0969-2126(97)00170-6 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.95 Å)

Structure validation