1OPC

OMPR DNA-BINDING DOMAIN, ESCHERICHIA COLI

1OPC の概要

• エントリーDOI: 10.2210/pdb1opc/pdb
• 分子名称: OMPR (2 entities in total)
• 機能のキーワード: transcription regulation, response regulator, winged helix, osmoregulation
• 由来する生物種: Escherichia coli
• 細胞内の位置: Cytoplasm: P0AA16
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 12538.37

構造登録者

Martinez-Hackert, E.,Stock, A.M. (登録日: 1996-12-16, 公開日: 1997-04-01, 最終更新日: 2024-02-14)

主引用文献

Martinez-Hackert, E.,Stock, A.M.
The DNA-binding domain of OmpR: crystal structures of a winged helix transcription factor.
Structure, 5:109-124, 1997

PubMed Abstract: The differential expression of the ompF and ompC genes is regulated by two proteins that belong to the two component family of signal transduction proteins: the histidine kinase, EnvZ, and the response regulator, OmpR. OmpR belongs to a subfamily of at least 50 response regulators with homologous C-terminal DNA-binding domains of approximately 98 amino acids. Sequence homology with DNA-binding proteins of known structure cannot be detected, and the lack of structural information has prevented understanding of many of this familys functional properties.

PubMed: 9016718
DOI: 10.1016/S0969-2126(97)00170-6

実験手法

X-RAY DIFFRACTION (1.95 Å)