1OP9

Complex of human lysozyme with camelid VHH HL6 antibody fragment

1OP9 の概要

• エントリーDOI: 10.2210/pdb1op9/pdb
• 分子名称: HL6 camel VHH fragment, Lysozyme C (3 entities in total)
• 機能のキーワード: antigen-antibody complex, immunoglobulin, amyloid fibril formation inhibition, hydrolase
• 由来する生物種: Camelus dromedarius (Arabian camel); 詳細
• 細胞内の位置: Secreted: P61626
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 27759.94

構造登録者

Dumoulin, M.,Last, A.M.,Desmyter, A.,Decanniere, K.,Canet, D.,Larsson, G.,Spencer, A.,Archer, D.B.,Sasse, J.,Muyldermans, S.,Wyns, L.,Redfield, C.,Matagne, A.,Robinson, C.V.,Dobson, C.M. (登録日: 2003-03-05, 公開日: 2003-10-14, 最終更新日: 2023-08-16)

• 主引用文献: Dumoulin, M.,Last, A.M.,Desmyter, A.,Decanniere, K.,Canet, D.,Larsson, G.,Spencer, A.,Archer, D.B.,Sasse, J.,Muyldermans, S.,Wyns, L.,Redfield, C.,Matagne, A.,Robinson, C.V.,Dobson, C.M.; A camelid antibody fragment inhibits the formation of amyloid fibrils by human lysozyme; Nature, 424:783-788, 2003; PubMed: 12917687; DOI: 10.1038/nature01870

実験手法

X-RAY DIFFRACTION (1.86 Å)