1OLX
Roles of His291-alpha and His146-beta' in the reductive acylation reaction catalyzed by human branched-chain alpha-ketoacid dehydrogenase
Summary for 1OLX
Entry DOI | 10.2210/pdb1olx/pdb |
Related | 1DTW 1OLS 1OLU |
Descriptor | 2-OXOISOVALERATE DEHYDROGENASE ALPHA SUBUNIT, 2-OXOISOVALERATE DEHYDROGENASE BETA SUBUNIT, POTASSIUM ION, ... (7 entities in total) |
Functional Keywords | oxidoreductase, ketoacid dehydrogenase, branched-chain, multi-enzyme complex, acylation, oxidative decarboxylation oxidoreductase, maple syrup urine disease, thiamine phosphate |
Biological source | HOMO SAPIENS (HUMAN) More |
Total number of polymer chains | 2 |
Total formula weight | 84148.94 |
Authors | Wynn, R.M.,Machius, M.,Chuang, J.L.,Li, J.,Tomchick, D.R.,Chuang, D.T. (deposition date: 2003-08-18, release date: 2003-08-28, Last modification date: 2023-12-13) |
Primary citation | Wynn, R.M.,Machius, M.,Chuang, J.L.,Li, J.,Tomchick, D.R.,Chuang, D.T. Roles of His291-Alpha and His146-Beta' in the Reductive Acylation Reaction Catalyzed by Human Branched-Chain Alpha-Ketoacid Dehydrogenase: Refined Phosphorylation Loop Structure in the Active Site. J.Biol.Chem., 278:43402-, 2003 Cited by PubMed: 12902323DOI: 10.1074/JBC.M306204200 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.25 Å) |
Structure validation
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