1OKN

CARBONIC ANHYDRASE II COMPLEX WITH THE 1OKN INHIBITOR 4-SULFONAMIDE-[1-(4-N-(5-FLUORESCEIN THIOUREA)BUTANE)]

Summary for 1OKN

• Entry DOI: 10.2210/pdb1okn/pdb
• Descriptor: CARBONIC ANHYDRASE II, MERCURY (II) ION, ZINC ION, ... (5 entities in total)
• Functional Keywords: lyase (oxo-acid), inhibitor, lyase
• Biological source: Homo sapiens (human)
• Cellular location: Cytoplasm: P00918
• Total number of polymer chains: 1
• Total formula weight: 29741.29

Authors

Elbaum, D.,Nair, S.K.,Patchan, M.W.,Thompson, R.B.,Christianson, D.W. (deposition date: 1996-06-25, release date: 1997-01-11, Last modification date: 2024-02-14)

• Primary citation: Elbaum, D.,Nair, S.K.,Patchan, M.W.,Thompson, R.B.,Christianson, D.W.; Structure-based design of a sulfonamide probe for fluorescence anisotropy detection of zinc with a carbonic anhydrase-based biosensor.; J.Am.Chem.Soc., 118:8381-8387, 1996

Experimental method

X-RAY DIFFRACTION (2.4 Å)