1OKM
CARBONIC ANHYDRASE II COMPLEX WITH THE 1OKM INHIBITOR 4-SULFONAMIDE-[1-(4-AMINOBUTANE)]BENZAMIDE
Summary for 1OKM
Entry DOI | 10.2210/pdb1okm/pdb |
Descriptor | CARBONIC ANHYDRASE II, MERCURY (II) ION, ZINC ION, ... (5 entities in total) |
Functional Keywords | lyase (oxo-acid), inhibitor, lyase |
Biological source | Homo sapiens (human) |
Cellular location | Cytoplasm: P00918 |
Total number of polymer chains | 1 |
Total formula weight | 29695.20 |
Authors | Elbaum, D.,Nair, S.K.,Patchan, M.W.,Thompson, R.B.,Christianson, D.W. (deposition date: 1996-06-25, release date: 1997-01-11, Last modification date: 2024-02-14) |
Primary citation | Elbaum, D.,Nair, S.K.,Patchan, M.W.,Thompson, R.B.,Christianson, D.W. Structure-based design of a sulfonamide probe for fluorescence anisotropy detection of zinc with a carbonic anhydrase-based biosensor. J.Am.Chem.Soc., 118:8381-8387, 1996 Cited by |
Experimental method | X-RAY DIFFRACTION (2.2 Å) |
Structure validation
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