1OJ8

Novel and retro Binding Modes in Cytotoxic Ribonucleases from Rana catesbeiana of Two Crystal Structures Complexed with d(ApCpGpA) and (2',5'CpG)

Summary for 1OJ8

Related1OJ1
DescriptorRC-RNASE6 RIBONUCLEASE, 5'-D(*AP*CP*GP*AP)-3', SULFATE ION, ... (4 entities in total)
Functional Keywordscytotoxic ribonucleases, anti-tumor activity, sialic binding and nucleotide binding, hydrolase
Biological sourceRANA CATESBEIANA (BULL FROG)
Total number of polymer chains2
Total molecular weight13577.36
Authors
Tsai, C.-J.,Liu, J.-H.,Liao, Y.-D.,Chen, L.-Y.,Cheng, P.-T.,Sun, Y.-J. (deposition date: 2003-07-07, release date: 2004-07-15, Last modification date: 2011-07-13)
Primary citation
Tsai, C.-J.,Liu, J.-H.,Liao, Y.-D.,Chen, L.-Y.,Cheng, P.-T.,Sun, Y.-J.
Retro and Novel Binding Modes in Cytotoxic Ribonucleases from Rana Catesbeiana of Two Crystal Structures Complexed with (2',5'Cpg) and D(Apcpgpa)
To be Published,
Experimental method
X-RAY DIFFRACTION (1.7 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.2781904.1%4.6%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution