1OGS

human acid-beta-glucosidase

1OGS の概要

• エントリーDOI: 10.2210/pdb1ogs/pdb
• 分子名称: Glucosylceramidase, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, SULFATE ION, ... (5 entities in total)
• 機能のキーワード: hydrolase, gaucher disease, glucosidase, glucocerebrosidase, cerezyme hydrolase, glycosidase, sphingolipid metabolism, glycoprote lysosome, membrane, disease mutati polymorphism, alternative initiation, pharmaceutical, israel structural proteomics center, ispc, structural genomics
• 由来する生物種: Homo sapiens (Human)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 113366.89

構造登録者

Dvir, H.,Harel, M.,McCarthy, A.A.,Toker, L.,Silman, I.,Futerman, A.H.,Sussman, J.L. (登録日: 2003-05-13, 公開日: 2003-07-03, 最終更新日: 2020-07-29)

• 主引用文献: Dvir, H.,Harel, M.,Mccarthy, A.A.,Toker, L.,Silman, I.,Futerman, A.H.,Sussman, J.L.; X-Ray Structure of Human Acid-Beta-Glucosidase, the Defective Enzyme in Gaucher Disease; Embo Rep., 4:704-, 2003; PubMed: 12792654; DOI: 10.1038/SJ.EMBOR.EMBOR873

実験手法

X-RAY DIFFRACTION (2 Å)