1O8T

Global Structure and Dynamics of Human Apolipoprotein CII in Complex with Micelles: Evidence for increased mobility of the helix involved in the activation of lipoprotein lipase

1O8T の概要

• エントリーDOI: 10.2210/pdb1o8t/pdb
• 関連するPDBエントリー: 1BY6 1I5J
• 分子名称: APOLIPOPROTEIN C-II (1 entity in total)
• 機能のキーワード: apocii, lpl, activation mechanism, domain motion, sds, micelle, global structure, local structure, dynamics, helix, lipid transport, lipid degradation, chylomicron
• 由来する生物種: HOMO SAPIENS (HUMAN)
• 細胞内の位置: Secreted: P02655
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 8921.86

構造登録者

Zdunek, J.,Martinez, G.V.,Schleucher, J.,Lycksell, P.O.,Yin, Y.,Nilsson, S.,Shen, Y.,Olivecrona, G.,Wijmenga, S. (登録日: 2002-11-29, 公開日: 2003-02-27, 最終更新日: 2011-07-13)

• 主引用文献: Zdunek, J.,Martinez, G.V.,Schleucher, J.,Lycksell, P.O.,Yin, Y.,Nilsson, S.,Shen, Y.,Olivecrona, G.,Wijmenga, S.; Global Structure and Dynamics of Human Apolipoprotein Cii in Complex with Micelles: Evidence for Increased Mobility of the Helix Involved in the Activation of Lipoprotein Lipase; Biochemistry, 42:1872-, 2003; PubMed: 12590574; DOI: 10.1021/BI0267184

実験手法

SOLUTION NMR