1O6I

Chitinase B from Serratia marcescens complexed with the catalytic intermediate mimic cyclic dipeptide CI4.

1O6I の概要

• エントリーDOI: 10.2210/pdb1o6i/pdb
• 関連するPDBエントリー: 1H0G 1H0I
• 分子名称: Chitinase, amino({3-[(3S,8aS)-1,4-dioxooctahydropyrrolo[1,2-a]pyrazin-3-yl]propyl}amino)methaniminium, GLYCEROL, ... (5 entities in total)
• 機能のキーワード: hydrolase-hydrolase inhibitor complex, chitinase, catalytic intermediate mimic, cyclic dipeptide, hydrolase- hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
• 由来する生物種: Serratia marcescens
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 114975.93

構造登録者

Houston, D.R.,Eggleston, I.,Synstad, B.,Eijsink, V.G.H.,van Aalten, D.M.F. (登録日: 2002-10-03, 公開日: 2003-03-30, 最終更新日: 2023-12-13)

• 主引用文献: Houston, D.R.,Eggleston, I.,Synstad, B.,Eijsink, V.G.,van Aalten, D.M.; The cyclic dipeptide CI-4 [cyclo-(l-Arg-d-Pro)] inhibits family 18 chitinases by structural mimicry of a reaction intermediate.; Biochem. J., 368:23-27, 2002; PubMed: 12323074; DOI: 10.1042/BJ20021034

実験手法

X-RAY DIFFRACTION (1.7 Å)