1O0M

Ribonuclease A in complex with uridine-2'-phosphate

1O0M の概要

• エントリーDOI: 10.2210/pdb1o0m/pdb
• 関連するPDBエントリー: 1O0F 1O0H 1O0N 1O0O
• 分子名称: Ribonuclease pancreatic, PHOSPHORIC ACID MONO-[2-(2,4-DIOXO-3,4-DIHYDRO-2H-PYRIMIDIN-1-YL)-4-HYDROXY-5-HYDROXYMETHYL-TETRAHYDRO-FURAN-3-YL] ESTER (3 entities in total)
• 機能のキーワード: hydrolase, ribonuclease
• 由来する生物種: Bos taurus (cattle)
• 細胞内の位置: Secreted: P61823
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 28065.01

構造登録者

Leonidas, D.D.,Oikonomakos, N.G.,Chrysina, E.D.,Kosmopoulou, M.N.,Vlassi, M. (登録日: 2003-02-24, 公開日: 2003-12-09, 最終更新日: 2023-10-25)

• 主引用文献: Leonidas, D.D.,Chavali, G.B.,Oikonomakos, N.G.,Chrysina, E.D.,Kosmopoulou, M.N.,Vlassi, M.,Frankling, C.,Acharya, K.R.; High-resolution crystal structures of ribonuclease A complexed with adenylic and uridylic nucleotide inhibitors. Implications for structure-based design of ribonucleolytic inhibitors; PROTEIN SCI., 12:2559-2574, 2003; PubMed: 14573867; DOI: 10.1110/ps.03196603

実験手法

X-RAY DIFFRACTION (1.5 Å)