1NXC

Structure of mouse Golgi alpha-1,2-mannosidase IA reveals the molecular basis for substrate specificity among Class I enzymes (family 47 glycosidases)

1NXC の概要

• エントリーDOI: 10.2210/pdb1nxc/pdb
• 分子名称: Mannosyl-oligosaccharide 1,2-alpha-mannosidase IA, alpha-D-mannopyranose-(1-6)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... (4 entities in total)
• 機能のキーワード: mannosidase, glycosidase, structural genomics, psi, protein structure initiative, southeast collaboratory for structural genomics, secsg, hydrolase
• 由来する生物種: Mus musculus (house mouse)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 55977.46

構造登録者

Tempel, W.,Liu, Z.-J.,Karaveg, K.,Rose, J.,Moremen, K.W.,Wang, B.-C.,Southeast Collaboratory for Structural Genomics (SECSG) (登録日: 2003-02-10, 公開日: 2004-05-04, 最終更新日: 2020-07-29)

• 主引用文献: Tempel, W.,Karaveg, K.,Liu, Z.-J.,Rose, J.,Wang, B.-C.,Moremen, K.W.; Structure of mouse Golgi alpha-mannosidase IA reveals the molecular basis for substrate specificity among class 1 (family 47 glycosylhydrolase) alpha1,2-mannosidases; J.Biol.Chem., 279:29774-29786, 2004; PubMed: 15102839; DOI: 10.1074/jbc.M403065200

実験手法

X-RAY DIFFRACTION (1.51 Å)