1NVB

Crystal structure of 3-dehydroquinate synthase (DHQS) in complex with ZN2+ and carbaphosphonate

Summary for 1NVB

• Entry DOI: 10.2210/pdb1nvb/pdb
• Related: 1NR5 1NRX 1NUA 1NVA 1NVD 1NVE 1NVF
• Descriptor: 3-DEHYDROQUINATE SYNTHASE, ZINC ION, CHLORIDE ION, ... (6 entities in total)
• Functional Keywords: shikimate pathway, aromatic amino acid biosynthesis, dhqs, closed form, form c, domain movement, cyclase, lyase
• Biological source: Emericella nidulans
• Cellular location: Cytoplasm: P07547
• Total number of polymer chains: 2
• Total formula weight: 87338.57

Authors

Nichols, C.E.,Ren, J.,Lamb, H.K.,Hawkins, A.R.,Stammers, D.K. (deposition date: 2003-02-03, release date: 2003-03-18, Last modification date: 2023-10-25)

• Primary citation: Nichols, C.E.,Ren, J.,Lamb, H.K.,Hawkins, A.R.,Stammers, D.K.; Ligand-induced Conformational Changes and a Mechanism for Domain Closure in Aspergillus nidulans Dehydroquinate Synthase; J.MOL.BIOL., 327:129-144, 2003; PubMed: 12614613; DOI: 10.1016/S0022-2836(03)00086-X

Experimental method

X-RAY DIFFRACTION (2.7 Å)