1NVB

Crystal structure of 3-dehydroquinate synthase (DHQS) in complex with ZN2+ and carbaphosphonate

1NVB の概要

• エントリーDOI: 10.2210/pdb1nvb/pdb
• 関連するPDBエントリー: 1NR5 1NRX 1NUA 1NVA 1NVD 1NVE 1NVF
• 分子名称: 3-DEHYDROQUINATE SYNTHASE, ZINC ION, CHLORIDE ION, ... (6 entities in total)
• 機能のキーワード: shikimate pathway, aromatic amino acid biosynthesis, dhqs, closed form, form c, domain movement, cyclase, lyase
• 由来する生物種: Emericella nidulans
• 細胞内の位置: Cytoplasm: P07547
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 87338.57

構造登録者

Nichols, C.E.,Ren, J.,Lamb, H.K.,Hawkins, A.R.,Stammers, D.K. (登録日: 2003-02-03, 公開日: 2003-03-18, 最終更新日: 2023-10-25)

• 主引用文献: Nichols, C.E.,Ren, J.,Lamb, H.K.,Hawkins, A.R.,Stammers, D.K.; Ligand-induced Conformational Changes and a Mechanism for Domain Closure in Aspergillus nidulans Dehydroquinate Synthase; J.MOL.BIOL., 327:129-144, 2003; PubMed: 12614613; DOI: 10.1016/S0022-2836(03)00086-X

実験手法

X-RAY DIFFRACTION (2.7 Å)