1NU1

Crystal Structure of Mitochondrial Cytochrome bc1 Complexed with 2-nonyl-4-hydroxyquinoline N-oxide (NQNO)

1NU1 の概要

• エントリーDOI: 10.2210/pdb1nu1/pdb
• 関連するPDBエントリー: 1NTK 1NTM 1NTZ
• 分子名称: Ubiquinol-cytochrome C reductase complex core protein I, mitochondrial, Ubiquinol-cytochrome C reductase complex 7.2 kDa protein, Ubiquinol-cytochrome C reductase complex 6.4 kDa protein, ... (15 entities in total)
• 機能のキーワード: bc1, qcr, membrane protein, proton translocation, electron transfer, protease, mpp, mitochondrial processing peptidase, cytochrome c1, cytochrome b, rieske, iron sulfur protein, oxidoreductase, 2-nonyl-4-hydroxyquinoline n-oxide (nqno)
• 由来する生物種: Bos taurus (cattle); 詳細
• 細胞内の位置: Mitochondrion inner membrane; Peripheral membrane protein; Matrix side: P31800 P23004; Mitochondrion inner membrane: P00130 P07552 P13272 P00129 P13271 P00126 P13272; Mitochondrion inner membrane; Multi-pass membrane protein (By similarity): P00157; Mitochondrion inner membrane; Single-pass membrane protein; Intermembrane side: P00125
• タンパク質・核酸の鎖数: 11
• 化学式量合計: 241507.70

構造登録者

Gao, X.,Wen, X.,Esser, L.,Quinn, B.,Yu, L.,Yu, C.-A.,Xia, D. (登録日: 2003-01-30, 公開日: 2003-10-07, 最終更新日: 2011-07-13)

• 主引用文献: Gao, X.,Wen, X.,Esser, L.,Quinn, B.,Yu, L.,Yu, C.-A.,Xia, D.; Structural basis for the quinone reduction in the bc(1) complex: a comparative analysis of crystal structures of mitochondrial cytochrome bc(1) with bound substrate and inhibitors at the Q(i) site; Biochemistry, 42:9067-9080, 2003; PubMed: 12885240; DOI: 10.1021/bi0341814

実験手法

X-RAY DIFFRACTION (3.2 Å)