1NSD

INFLUENZA B VIRUS NEURAMINIDASE CAN SYNTHESIZE ITS OWN INHIBITOR

Summary for 1NSD

• Entry DOI: 10.2210/pdb1nsd/pdb
• Descriptor: NEURAMINIDASE, 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... (5 entities in total)
• Functional Keywords: o-glycosyl, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
• Biological source: Influenza B virus (STRAIN B/BEIJING/1/87)
• Total number of polymer chains: 2
• Total formula weight: 88003.67

Authors

Burmeister, W.P.,Ruigrok, R.W.H.,Cusack, S. (deposition date: 1993-05-24, release date: 1993-10-31, Last modification date: 2024-11-06)

Primary citation

Burmeister, W.P.,Henrissat, B.,Bosso, C.,Cusack, S.,Ruigrok, R.W.
Influenza B virus neuraminidase can synthesize its own inhibitor.
Structure, 1:19-26, 1993

PubMed Abstract: Neuraminidase, one of the two surface glycoproteins of influenza virus, cleaves terminal sialic acid residues from glycolipids or glycoproteins. Its crystal structure is known at high resolution, but the mechanism of glycosyl hydrolysis remains unclear.

PubMed: 8069621
DOI: 10.1016/0969-2126(93)90005-2

Experimental method

X-RAY DIFFRACTION (1.8 Å)