1NMX

Crystal structure of human thymidylate kinase with FLTMP and ADP

Summary for 1NMX

Entry DOI	10.2210/pdb1nmx/pdb
Descriptor	similar to THYMIDYLATE KINASE (DTMP KINASE), MAGNESIUM ION, 3'-FLUORO-3'-DEOXYTHYMIDINE MONOPHOSPHATE, ... (5 entities in total)
Functional Keywords	thymidylate kinase, p-loop, fluorothymidine, transferase
Biological source	Homo sapiens (human)
Total number of polymer chains	1
Total formula weight	24852.54
Authors	Ostermann, N.,Segura-Pena, D.,Meier, C.,Veit, T.,Monnerjahn, M.,Konrad, M.,Lavie, A. (deposition date: 2003-01-12, release date: 2003-03-18, Last modification date: 2024-02-14)
Primary citation	Ostermann, N.,Segura-Pena, D.,Meier, C.,Veit, T.,Monnerjahn, M.,Konrad, M.,Lavie, A. Structures of human thymidylate kinase in complex with prodrugs: implications for the structure-based design of novel compounds Biochemistry, 42:2568-2577, 2003 Cited by PubMed: 12614151 DOI: 10.1021/bi027302t PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.7 Å)

Structure validation