1NER
SOLUTION STRUCTURE OF THE MU NER PROTEIN BY MULTIDIMENSIONAL NMR
Summary for 1NER
| Entry DOI | 10.2210/pdb1ner/pdb |
| Descriptor | DNA-BINDING PROTEIN NER (1 entity in total) |
| Functional Keywords | dna-binding protein, dna binding protein |
| Biological source | Enterobacteria phage Mu |
| Total number of polymer chains | 1 |
| Total formula weight | 8388.54 |
| Authors | Clore, G.M.,Strzelecka, T.E.,Gronenborn, A.M. (deposition date: 1995-08-24, release date: 1995-12-07, Last modification date: 2024-05-22) |
| Primary citation | Strzelecka, T.E.,Clore, G.M.,Gronenborn, A.M. The solution structure of the Mu Ner protein reveals a helix-turn-helix DNA recognition motif. Structure, 3:1087-1095, 1995 Cited by PubMed Abstract: The Mu Ner protein is a small (74 amino acids), basic, DNA-binding protein found in phage Mu. It belongs to a class of proteins, the cro and repressor proteins, that regulate the switch from the lysogenic to the lytic state of the phage life cycle. There is no significant sequence identity between Mu Ner and the cro proteins of other phages, despite their functional similarity. In addition, there is no significant sequence identity with any other DNA-binding proteins, with the exception of Ner from the related phage D108 and the Nlp protein of Escherichia coli. As the tertiary structures of Mu Ner and these two related proteins are unknown, it is clear that a three-dimensional (3D) structure of Mu Ner is essential in order to gain insight into its mode of DNA binding. PubMed: 8590003DOI: 10.1016/S0969-2126(01)00244-1 PDB entries with the same primary citation |
| Experimental method | SOLUTION NMR |
Structure validation
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