1NE6

Crystal structure of Sp-cAMP binding R1a subunit of cAMP-dependent protein kinase

1NE6 の概要

• エントリーDOI: 10.2210/pdb1ne6/pdb
• 関連するPDBエントリー: 1CX4 1NE4 1RGS
• 分子名称: cAMP-dependent protein kinase type I-alpha regulatory chain, 6-(6-AMINO-PURIN-9-YL)-2-THIOXO-TETRAHYDRO-2-FURO[3,2-D][1,3,2]DIOXAPHOSPHININE-2,7-DIOL (3 entities in total)
• 機能のキーワード: camp-dependent protein kinase, r1a subunit, camp analog, sp-camp, hydrolase
• 由来する生物種: Bos taurus (cattle)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 32570.65

構造登録者

Wu, J.,Jones, J.M.,Xuong, N.H.,Taylor, S.S. (登録日: 2002-12-10, 公開日: 2004-01-13, 最終更新日: 2023-08-16)

• 主引用文献: Wu, J.,Jones, J.M.,Xuong, N.H.,Eyck, L.F.,Taylor, S.S.; Crystal Structures of RIalpha Subunit of Cyclic Adenosine 5'-Monophosphate (cAMP)-Dependent Protein Kinase Complexed with (R(p))-Adenosine 3',5'-Cyclic Monophosphothioate and (S(p))-Adenosine 3',5'-Cyclic Monophosphothioate, the Phosphothioate Analogues of cAMP.; Biochemistry, 43:6620-6629, 2004; PubMed: 15157095; DOI: 10.1021/bi0302503

実験手法

X-RAY DIFFRACTION (2.3 Å)