1NAB
The crystal structure of the complex between a disaccharide anthracycline and the DNA hexamer d(CGATCG) reveals two different binding sites involving two DNA duplexes
1NAB の概要
エントリーDOI | 10.2210/pdb1nab/pdb |
分子名称 | 5'-D(*CP*GP*AP*TP*CP*G)-3', 7-[5-(4-AMINO-5-HYDROXY-6-METHYL-TETRAHYDRO-PYRAN-2-YLOXY)-4-HYDROXY-6-METHYL-TETRAHYDRO-PYRAN-2-YLOXY]-6,9,11-TRIHYDROXY-9-(2-HYDROXY-ACETYL)-7,8,9,10-TETRAHYDRO-NAPHTHACENE-5,12-DIONE (3 entities in total) |
機能のキーワード | right handed dna, double helix, complexed with drug, dna |
タンパク質・核酸の鎖数 | 2 |
化学式量合計 | 4905.70 |
構造登録者 | Temperini, C.,Messori, L.,Orioli, P.,Di Bugno, C.,Animati, F.,Ughetto, G. (登録日: 2002-11-27, 公開日: 2003-02-25, 最終更新日: 2024-02-14) |
主引用文献 | Temperini, C.,Messori, L.,Orioli, P.,Di Bugno, C.,Animati, F.,Ughetto, G. The crystal structure of the complex between a disaccharide anthracycline and the DNA hexamer d(CGATCG) reveals two different binding sites involving two DNA duplexes Nucleic Acids Res., 31:1464-1469, 2003 Cited by PubMed: 12595554DOI: 10.1093/nar/gkg245 主引用文献が同じPDBエントリー |
実験手法 | X-RAY DIFFRACTION (2.15 Å) |
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