1N5X

Xanthine Dehydrogenase from Bovine Milk with Inhibitor TEI-6720 Bound

Summary for 1N5X

Entry DOI	10.2210/pdb1n5x/pdb
Related	1FIQ 1FO4
Descriptor	Xanthine Dehydrogenase, FE2/S2 (INORGANIC) CLUSTER, PHOSPHONIC ACIDMONO-(2-AMINO-5,6-DIMERCAPTO-4-OXO-3,7,8A,9,10,10A-HEXAHYDRO-4H-8-OXA-1,3,9,10-TETRAAZA-ANTHRACEN-7-YLMETHYL)ESTER, ... (6 entities in total)
Functional Keywords	oxidoreductase, molybdopterin, tei-6720, flavoprotein, fad, iron-sulfur center, fe2/s2 center
Biological source	Bos taurus (cattle)
Cellular location	Cytoplasm (By similarity): P80457
Total number of polymer chains	2
Total formula weight	297743.76
Authors	Okamoto, K.,Eger, B.T.,Nishino, T.,Kondo, S.,Pai, E.F.,Nishino, T. (deposition date: 2002-11-07, release date: 2003-03-18, Last modification date: 2023-10-25)
Primary citation	Okamoto, K.,Eger, B.T.,Nishino, T.,Kondo, S.,Pai, E.F.,Nishino, T. An Extremely Potent Inhibitor of Xanthine Oxidoreductase: Crystal Structure of the Enzyme-Inhibitor Complex and Mechanism of Inhibition J.BIOL.CHEM., 278:1848-1855, 2003 Cited by PubMed: 12421831 DOI: 10.1074/jbc.M208307200 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.8 Å)

Structure validation