1N5X

Xanthine Dehydrogenase from Bovine Milk with Inhibitor TEI-6720 Bound

1N5X の概要

• エントリーDOI: 10.2210/pdb1n5x/pdb
• 関連するPDBエントリー: 1FIQ 1FO4
• 分子名称: Xanthine Dehydrogenase, FE2/S2 (INORGANIC) CLUSTER, PHOSPHONIC ACIDMONO-(2-AMINO-5,6-DIMERCAPTO-4-OXO-3,7,8A,9,10,10A-HEXAHYDRO-4H-8-OXA-1,3,9,10-TETRAAZA-ANTHRACEN-7-YLMETHYL)ESTER, ... (6 entities in total)
• 機能のキーワード: oxidoreductase, molybdopterin, tei-6720, flavoprotein, fad, iron-sulfur center, fe2/s2 center
• 由来する生物種: Bos taurus (cattle)
• 細胞内の位置: Cytoplasm (By similarity): P80457
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 297743.76

構造登録者

Okamoto, K.,Eger, B.T.,Nishino, T.,Kondo, S.,Pai, E.F.,Nishino, T. (登録日: 2002-11-07, 公開日: 2003-03-18, 最終更新日: 2023-10-25)

• 主引用文献: Okamoto, K.,Eger, B.T.,Nishino, T.,Kondo, S.,Pai, E.F.,Nishino, T.; An Extremely Potent Inhibitor of Xanthine Oxidoreductase: Crystal Structure of the Enzyme-Inhibitor Complex and Mechanism of Inhibition; J.BIOL.CHEM., 278:1848-1855, 2003; PubMed: 12421831; DOI: 10.1074/jbc.M208307200

実験手法

X-RAY DIFFRACTION (2.8 Å)