1MZI

Solution ensemble structures of HIV-1 gp41 2F5 mAb epitope

1MZI の概要

• エントリーDOI: 10.2210/pdb1mzi/pdb
• 分子名称: 2F5 epitope of HIV-1 gp41 fusion protein (1 entity in total)
• 機能のキーワード: ensemble, statistics, viral protein
• 細胞内の位置: Transmembrane protein gp41: Virion membrane; Single-pass type I membrane protein. Surface protein gp120: Virion membrane; Peripheral membrane protein: P04578
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 1617.82

構造登録者

Barbato, G.,Bianchi, E.,Ingallinella, P.,Hurni, W.H.,Miller, M.D.,Ciliberto, G.,Cortese, R.,Bazzo, R.,Shiver, J.W.,Pessi, A. (登録日: 2002-10-08, 公開日: 2003-09-02, 最終更新日: 2024-05-29)

• 主引用文献: Barbato, G.,Bianchi, E.,Ingallinella, P.,Hurni, W.H.,Miller, M.D.,Ciliberto, G.,Cortese, R.,Bazzo, R.,Shiver, J.W.,Pessi, A.; Structural analysis of the epitope of the anti-HIV antibody 2F5 sheds light into its mechanism of neutralization and HIV fusion.; J.Mol.Biol., 330:1101-1115, 2003; PubMed: 12860131; DOI: 10.1016/S0022-2836(03)00611-9

実験手法

SOLUTION NMR