1MY6

The 1.6 A Structure of Fe-Superoxide Dismutase from the thermophilic cyanobacterium Thermosynechococcus elongatus : Correlation of EPR and Structural Characteristics

1MY6 の概要

• エントリーDOI: 10.2210/pdb1my6/pdb
• 分子名称: Iron (III) Superoxide Dismutase, FE (III) ION (3 entities in total)
• 機能のキーワード: iron speroxide dismutase, thermophile, reactive oxygen species, cyanobacteria, thermosynechococcus, thermosynechococcus elongatus, superoxide dismutase, sod, fesod, iron(iii) superoxide dismutase, oxidoreductase
• 由来する生物種: Thermosynechococcus elongatus
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 44324.89

構造登録者

Yoshida, S.M.,Cascio, D.,Sawaya, M.R.,Yeates, T.O.,Kerfeld, C.A. (登録日: 2002-10-03, 公開日: 2003-07-29, 最終更新日: 2024-02-14)

主引用文献

Kerfeld, C.A.,Yoshida, S.,Tran, K.T.,Yeates, T.O.,Cascio, D.,Bottin, H.,Berthomieu, C.,Sugiura, M.,Boussac, A.
The 1.6 A resolution structure of Fe-superoxide dismutase from the thermophilic cyanobacterium Thermosynechococcus elongatus.
J.BIOL.INORG.CHEM., 8:707-714, 2003

PubMed Abstract: The iron-containing superoxide dismutase (FeSOD) from the thermophilic cyanobacterium Thermosynechococcus elongatus has been isolated. The protein crystallizes readily and we have determined the structure to 1.6 A resolution. This is the first structural characterization of an FeSOD isolated from a cyanobacterium and one of the highest resolution FeSOD structures determined to date. The activity of the T. elongatus FeSOD has been measured both at 25 degrees C and 50 degrees C and it has been spectroscopically characterized. The T. elongatus FeSOD EPR spectra at pH 5.1, 7.5 and 10.0 are similar. This indicates that no change in the geometry of the Fe(III) site occurs over a wide range of pH. This is in contrast to the other FeSODs described in the literature.

PubMed: 12827458
DOI: 10.1007/s00775-003-0469-0

実験手法

X-RAY DIFFRACTION (1.6 Å)