1MXJ

NMR solution structure of benz[a]anthracene-dG in ras codon 12,2; GGCAGXTGGTG

1MXJ の概要

• エントリーDOI: 10.2210/pdb1mxj/pdb
• 分子名称: 5'-D(*GP*GP*CP*AP*GP*GP*TP*GP*GP*TP*G)-3', 5'-D(*CP*AP*CP*CP*AP*CP*CP*TP*GP*CP*C)-3', 1S,2R,3S,4R-TETRAHYDRO-BENZO[A]ANTHRACENE-2,3,4-TRIOL (3 entities in total)
• 機能のキーワード: dna adduct, b-like dna, dna
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 6989.70

構造登録者

Kim, H.-Y.H.,Wilkinson, A.S.,Harris, C.M.,Harris, T.M.,Stone, M.P. (登録日: 2002-10-02, 公開日: 2003-03-11, 最終更新日: 2022-02-23)

• 主引用文献: Kim, H.-Y.H.,Wilkinson, A.S.,Harris, C.M.,Harris, T.M.,Stone, M.P.; Minor Groove Orientation for the (1S,2R,3S,4R)-N2-[1-(1,2,3,4-tetrahydro-2,3,4-trihydroxy-benz[a]anthracenyl)]-2'-deoxyguanosyl Adduct in the N-ras Codon 12 sequence; Biochemistry, 42:2328-2338, 2003; PubMed: 12600200; DOI: 10.1021/bi020462k

実験手法

SOLUTION NMR