1MX2
Structure of F71N mutant of p18INK4c
Summary for 1MX2
| Entry DOI | 10.2210/pdb1mx2/pdb |
| Related | 1MX4 1MX6 |
| Descriptor | Cyclin-dependent kinase 6 inhibitor (2 entities in total) |
| Functional Keywords | ankyrin repeats, cell cycle inhibitor |
| Biological source | Homo sapiens (human) |
| Total number of polymer chains | 2 |
| Total formula weight | 36232.57 |
| Authors | Marmorstein, R.,Venkataramani, R.N.,MacLachlan, T.K.,Chai, X.,El-Deiery, W.S. (deposition date: 2002-10-01, release date: 2002-10-16, Last modification date: 2024-02-14) |
| Primary citation | Venkataramani, R.N.,MacLachlan, T.K.,Chai, X.,El-Deiry, W.S.,Marmorstein, R. Structure-based design of p18INK4c proteins with increased thermodynamic stability and cell cycle inhibitory activity J.Biol.Chem., 277:48827-48833, 2002 Cited by PubMed: 12370184DOI: 10.1074/jbc.M208061200 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.25 Å) |
Structure validation
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