1MQE

Structure of the MT-ADPRase in complex with gadolidium and ADP-ribose, a Nudix enzyme

Summary for 1MQE

Entry DOI	10.2210/pdb1mqe/pdb
Related	1mk1 1mp2 1MQW 1MR2
Descriptor	ADPR pyrophosphatase, ADENOSINE-5-DIPHOSPHORIBOSE, GADOLINIUM ION, ... (4 entities in total)
Functional Keywords	nudix hydrolase, rv1700, adpr, mycobacterium tuberculosis, hydrolase
Biological source	Mycobacterium tuberculosis
Total number of polymer chains	1
Total formula weight	23637.41
Authors	Kang, L.-W.,Gabelli, S.B.,Bianchet, M.A.,Cunningham, J.E.,O'Handley, S.F.,Amzel, L.M. (deposition date: 2002-09-16, release date: 2003-08-05, Last modification date: 2024-02-14)
Primary citation	Kang, L.-W.,Gabelli, S.B.,Cunningham, J.E.,O'Handley, S.F.,Amzel, L.M. Structure and mechanism of MT-ADPRase, a Nudix hydrolase from Mycobacterium tuberculosis Structure, 11:1015-1023, 2003 Cited by PubMed Abstract: Nudix hydrolases are a family of proteins that contain the characteristic sequence GX(5)EX(7)REUXEEXG(I/L/V), the Nudix box. They catalyze the hydrolysis of a variety of nucleoside diphosphate derivatives such as ADP-ribose, Ap(n)A (3 PubMed: 12906832 DOI: 10.1016/S0969-2126(03)00154-0 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2 Å)

Structure validation