1MPO

MALTOPORIN MALTOHEXAOSE COMPLEX

Summary for 1MPO

• Entry DOI: 10.2210/pdb1mpo/pdb
• Related PRD ID: PRD_900030
• Descriptor: MALTOPORIN, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose, MAGNESIUM ION, ... (4 entities in total)
• Functional Keywords: membrane protein, specific porin, beta barrel membrane protein, sugar transport, beta barrel
• Biological source: Escherichia coli
• Cellular location: Cell outer membrane ; Multi-pass membrane protein : P02943
• Total number of polymer chains: 3
• Total formula weight: 144836.43

Authors

Dutzler, R.,Schirmer, T. (deposition date: 1996-01-11, release date: 1997-03-12, Last modification date: 2024-11-20)

Primary citation

Dutzler, R.,Wang, Y.F.,Rizkallah, P.J.,Rosenbusch, J.P.,Schirmer, T.
Crystal structures of various maltooligosaccharides bound to maltoporin reveal a specific sugar translocation pathway.
Structure, 4:127-134, 1996

PubMed Abstract: Maltoporin (which is encoded by the lamB gene) facilitates the translocation of maltodextrins across the outer membrane of E. coli. In particular, it is indispensable for the transport of long maltooligosaccharides, as these do not pass through non-specific porins. An understanding of this intriguing capability requires elucidation of the structural basis.

PubMed: 8805519
DOI: 10.1016/S0969-2126(96)00016-0

Experimental method

X-RAY DIFFRACTION (2.8 Å)