1MPN

MALTOPORIN MALTOTRIOSE COMPLEX

1MPN の概要

• エントリーDOI: 10.2210/pdb1mpn/pdb
• 関連するBIRD辞書のPRD_ID: PRD_900009
• 分子名称: MALTOPORIN, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose, MAGNESIUM ION (3 entities in total)
• 機能のキーワード: membrane protein, sugar transport, specific porin, beta barrel
• 由来する生物種: Escherichia coli
• 細胞内の位置: Cell outer membrane ; Multi-pass membrane protein : P02943
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 143863.58

構造登録者

Dutzler, R.,Schirmer, T. (登録日: 1996-01-11, 公開日: 1997-03-12, 最終更新日: 2020-07-29)

主引用文献

Dutzler, R.,Wang, Y.F.,Rizkallah, P.J.,Rosenbusch, J.P.,Schirmer, T.
Crystal structures of various maltooligosaccharides bound to maltoporin reveal a specific sugar translocation pathway.
Structure, 4:127-134, 1996

PubMed Abstract: Maltoporin (which is encoded by the lamB gene) facilitates the translocation of maltodextrins across the outer membrane of E. coli. In particular, it is indispensable for the transport of long maltooligosaccharides, as these do not pass through non-specific porins. An understanding of this intriguing capability requires elucidation of the structural basis.

PubMed: 8805519
DOI: 10.1016/S0969-2126(96)00016-0

実験手法

X-RAY DIFFRACTION (3.2 Å)