1MOF
COAT PROTEIN
Summary for 1MOF
| Entry DOI | 10.2210/pdb1mof/pdb |
| Descriptor | MOLONEY MURINE LEUKEMIA VIRUS P15, CHLORIDE ION (3 entities in total) |
| Functional Keywords | glycoprotein, coat protein, polyprotein, transmembrane, sign, viral protein |
| Biological source | Moloney murine leukemia virus |
| Total number of polymer chains | 1 |
| Total formula weight | 6204.50 |
| Authors | Fass, D.,Harrison, S.C.,Kim, P.S. (deposition date: 1996-04-02, release date: 1996-10-14, Last modification date: 2024-10-30) |
| Primary citation | Fass, D.,Harrison, S.C.,Kim, P.S. Retrovirus envelope domain at 1.7 angstrom resolution. Nat.Struct.Biol., 3:465-469, 1996 Cited by PubMed Abstract: We report the crystal structure of an extraviral segment of a retrovirus envelope protein, the Moloney murine leukemia virus (MoMuLV) transmembrane (TM) subunit. This segment, which comprises a region of the MoMuLV TM protein analogous to that contained within the X-ray crystal structure of low-pH converted influenza hemagglutinin, contains a trimeric coiled coil, with a hydrophobic cluster at its base and a strand that packs in an antiparallel orientation against the coiled coil. This structure gives the first high-resolution insight into the retrovirus surface and serves as a model for a wide range of viral fusion proteins; key residues in this structure are conserved among C- and D-type retroviruses and the filovirus ebola. PubMed: 8612078DOI: 10.1038/nsb0596-465 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.7 Å) |
Structure validation
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