1MK6

SOLUTION STRUCTURE OF THE 8,9-DIHYDRO-8-(N7-GUANYL)-9-HYDROXY-AFLATOXIN B1 ADDUCT MISPAIRED WITH DEOXYADENOSINE

Summary for 1MK6

• Entry DOI: 10.2210/pdb1mk6/pdb
• Related: 1MKL
• Descriptor: 5'-D(*AP*CP*AP*TP*CP*GP*AP*TP*CP*T)-3', 5'-D(*AP*GP*AP*TP*AP*GP*AP*TP*GP*T)-3', 8,9-DIHYDRO-9-HYDROXY-AFLATOXIN B1 (3 entities in total)
• Functional Keywords: aflatoxin b1- guanine adduct opposite an adenine, mimicking ga transition, dna
• Biological source: synthetic construct; More
• Total number of polymer chains: 2
• Total formula weight: 6442.35

Authors

Giri, I.,Johnston, D.S.,Stone, M.P. (deposition date: 2002-08-28, release date: 2002-10-16, Last modification date: 2024-05-01)

• Primary citation: Giri, I.,Johnston, D.S.,Stone, M.P.; MISPAIRING OF THE 8,9-DIHYDRO-8-(N7-GUANYL)-9-HYDROXY-AFLATOXIN B1 ADDUCT WITH DEOXYADENOSINE RESULTS IN EXTRUSION OF THE MISMATCHED DA TOWARD THE MAJOR GROOVE; Biochemistry, 41:5462-5472, 2002; PubMed: 11969407; DOI: 10.1021/bi012116t

Experimental method

SOLUTION NMR