1MEC

CONFORMATIONAL VARIABILITY OF A PICORNAVIRUS CAPSID: PH-DEPENDENT STRUCTURAL CHANGES OF MENGO VIRUS RELATED TO ITS HOST RECEPTOR ATTACHMENT SITE AND DISASSEMBLY

1MEC の概要

• エントリーDOI: 10.2210/pdb1mec/pdb
• 分子名称: MENGO VIRUS COAT PROTEIN (SUBUNIT VP1), MENGO VIRUS COAT PROTEIN (SUBUNIT VP2), PHOSPHATE ION, ... (6 entities in total)
• 機能のキーワード: cardio picornavirus coat protein, icosahedral virus, virus
• 由来する生物種: Mengo virus; 詳細
• 細胞内の位置: Protein 2A: Host nucleus . Protein VP2: Virion. Protein VP3: Virion. Protein VP1: Virion. Protein 2B: Host cytoplasmic vesicle membrane ; Peripheral membrane protein ; Cytoplasmic side . Protein 2C: Host cytoplasmic vesicle membrane ; Peripheral membrane protein ; Cytoplasmic side . Protein 3A: Host cytoplasmic vesicle membrane ; Peripheral membrane protein ; Cytoplasmic side . Protein 3B: Virion . Protease 3C: Host cytoplasm . RNA-directed RNA polymerase 3D-POL: Host cytoplasmic vesicle membrane ; Peripheral membrane protein ; Cytoplasmic side : P12296 P12296 P12296 P12296
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 91778.61

構造登録者

Rossmann, M.G. (登録日: 1992-01-17, 公開日: 1994-01-31, 最終更新日: 2023-04-19)

• 主引用文献: Kim, S.,Boege, U.,Krishnaswamy, S.,Minor, I.,Smith, T.J.,Luo, M.,Scraba, D.G.,Rossmann, M.G.; Conformational variability of a picornavirus capsid: pH-dependent structural changes of Mengo virus related to its host receptor attachment site and disassembly.; Virology, 175:176-190, 1990; PubMed: 2155508; DOI: 10.1016/0042-6822(90)90198-Z

実験手法

X-RAY DIFFRACTION (3.2 Å)