1MC0

Regulatory Segment of Mouse 3',5'-Cyclic Nucleotide Phosphodiesterase 2A, Containing the GAF A and GAF B Domains

1MC0 の概要

• エントリーDOI: 10.2210/pdb1mc0/pdb
• 分子名称: 3',5'-cyclic nucleotide phosphodiesterase 2A, CYCLIC GUANOSINE MONOPHOSPHATE (3 entities in total)
• 機能のキーワード: gaf domain, 3', 5'-cyclic nucleotide phosphodiesterase, 5'-guanosine monophosphate, hydrolase
• 由来する生物種: Mus musculus (house mouse)
• 細胞内の位置: Membrane; Peripheral membrane protein (Potential): Q922S4
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 41769.12

構造登録者

Martinez, S.,Wu, A.,Glavas, N.,Tang, X.,Turley, S.,Hol, W.,Beavo, J. (登録日: 2002-08-04, 公開日: 2002-10-02, 最終更新日: 2011-07-13)

• 主引用文献: Martinez, S.E.,Wu, A.Y.,Glavas, N.A.,Tang, X.B.,Turley, S.,Hol, W.G.,Beavo, J.A.; The two GAF domains in phosphodiesterase 2A have distinct roles in dimerization and in cGMP binding.; Proc.Natl.Acad.Sci.USA, 99:13260-13265, 2002; PubMed: 12271124; DOI: 10.1073/pnas.192374899

実験手法

X-RAY DIFFRACTION (2.86 Å)