1M8E

inducible nitric oxide synthase with 7-nitroindazole bound

Summary for 1M8E

Entry DOI	10.2210/pdb1m8e/pdb
Related	1M8D 1M8H 1M8I 1M9J 1M9K 1M9M 1M9Q 1M9R 1M9T 1NOD 3NOD
Descriptor	inducible Nitric oxide synthase, PROTOPORPHYRIN IX CONTAINING FE, 5,6,7,8-TETRAHYDROBIOPTERIN, ... (5 entities in total)
Functional Keywords	oxidoreductase
Biological source	Mus musculus (house mouse)
Total number of polymer chains	2
Total formula weight	102457.79
Authors	Rosenfeld, R.J.,Garcin, E.D.,Panda, K.,Andersson, G.,Aberg, A.,Wallace, A.V.,Stuehr, D.J.,Tainer, J.A.,Getzoff, E.D. (deposition date: 2002-07-24, release date: 2002-08-07, Last modification date: 2024-02-14)
Primary citation	Rosenfeld, R.J.,Garcin, E.D.,Panda, K.,Andersson, G.,Aberg, A.,Wallace, A.V.,Morris, G.M.,Olson, A.J.,Stuehr, D.J.,Tainer, J.A.,Getzoff, E.D. Conformational Changes in Nitric Oxide Synthases Induced by Chlorzoxazone and Nitroindazoles: Crystallographic and Computational Analyses of Inhibitor Potency Biochemistry, 41:13915-13925, 2002 Cited by PubMed: 12437348 DOI: 10.1021/bi026313j PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.9 Å)

Structure validation