1M8D

inducible nitric oxide synthase with Chlorzoxazone bound

Summary for 1M8D

Entry DOI	10.2210/pdb1m8d/pdb
Related	1M8E 1M8I 1M9J 1M9K 1M9M 1M9Q 1M9R 1M9T 1MIH 1NOD 3NOD
Descriptor	Inducible Nitric Oxide Synthase, SULFATE ION, PROTOPORPHYRIN IX CONTAINING FE, ... (8 entities in total)
Functional Keywords	inhibitor-induced conformational change, oxidoreductase
Biological source	Mus musculus (house mouse)
Total number of polymer chains	2
Total formula weight	103017.22
Authors	Rosenfeld, R.J.,Garcin, E.D.,Panda, K.,Andersson, G.,Aberg, A.,Wallace, A.V.,Stuehr, D.J.,Tainer, J.A.,Getzoff, E.D. (deposition date: 2002-07-24, release date: 2002-08-14, Last modification date: 2024-02-14)
Primary citation	Rosenfeld, R.J.,Garcin, E.D.,Panda, K.,Andersson, G.,Aberg, A.,Wallace, A.V.,Morris, G.M.,Olson, A.J.,Stuehr, D.J.,Tainer, J.A.,Getzoff, E.D. Conformational Changes in Nitric Oxide Synthases Induced by Chlorzoxazone and Nitroindazoles: Crystallographic and Computational Analyses of Inhibitor Potency Biochemistry, 41:13915-13925, 2002 Cited by PubMed: 12437348 DOI: 10.1021/bi026313j PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.35 Å)

Structure validation