1M69

Atomic Resolution Structure of 5Br-9amino-DACA with d[CGTACG]2

Summary for 1M69

• Entry DOI: 10.2210/pdb1m69/pdb
• Descriptor: 5'-D(*CP*GP*TP*AP*CP*G)-3', 5-BROMO-N[2-(DIMETHYLAMINO)ETHYL]-9-AMINOACRIDINE-4-CARBOXAMIDE, SPERMINE, ... (4 entities in total)
• Functional Keywords: atomic resolution, adenine-thymine disorder, topoisomerase ii poison, dna
• Total number of polymer chains: 1
• Total formula weight: 2790.14

Authors

Teixeira, S.C.M.,Thorpe, J.H.,Todd, A.K.,Cardin, C.J. (deposition date: 2002-07-15, release date: 2003-08-19, Last modification date: 2024-04-03)

• Primary citation: Teixeira, S.C.M.,Thorpe, J.H.,Todd, A.K.,Cardin, C.J.; Heavy Going: the Atomic Resolution Structure of a Topoisomerase II Poison Intercalating into DNA in Multiple Orientations Also Reveals a Multiple Adenine-Thymine Hydrogen Bonding Pattern; To be Published,

Experimental method

X-RAY DIFFRACTION (1.1 Å)