1LZZ

Rat neuronal NOS heme domain with N-isopropyl-N'-hydroxyguanidine bound

Summary for 1LZZ

Related1LZZ 1M00
DescriptorNitric-oxide synthase, ACETATE ION, ZINC ION, ... (7 entities in total)
Functional Keywordsnitric oxide synthase, oxydoreductase, heme-enzyme, oxidoreductase
Biological sourceRattus norvegicus (Norway rat)
Cellular locationCell membrane, sarcolemma; Peripheral membrane protein (By similarity) P29476
Total number of polymer chains2
Total molecular weight99243.7
Authors
Li, H.,Shimizu, H.,Flinspach, M.,Jamal, J.,Yang, W.,Xian, M.,Cai, T.,Wen, E.Z.,Jia, Q.,Wang, P.G.,Poulos, T.L. (deposition date: 2002-06-11, release date: 2002-11-27, Last modification date: 2011-07-13)
Primary citation
Li, H.,Shimizu, H.,Flinspach, M.,Jamal, J.,Yang, W.,Xian, M.,Cai, T.,Wen, E.Z.,Jia, Q.,Wang, P.G.,Poulos, T.L.
The Novel Binding Mode of N-Alkyl-N'-Hydroxyguanidine to Neuronal Nitric Oxide Synthase Provides Mechanistic Insights into NO Biosynthesis
Biochemistry, 41:13868-13875, 2002
PubMed: 12437343 (PDB entries with the same primary citation)
DOI: 10.1021/bi020417c
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.05 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.257120.2%2.2%8.4%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

Molmil generated image of 1lzz
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Molmil generated image of 1lzz
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Molmil generated image of 1lzz
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