1LZS

STRUCTURAL CHANGES OF THE ACTIVE SITE CLEFT AND DIFFERENT SACCHARIDE BINDING MODES IN HUMAN LYSOZYME CO-CRYSTALLIZED WITH HEXA-N-ACETYL-CHITOHEXAOSE AT PH 4.0

Summary for 1LZS

Entry DOI	10.2210/pdb1lzs/pdb
Descriptor	HUMAN LYSOZYME, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (5 entities in total)
Functional Keywords	hydrolase (o-glycosyl)
Biological source	Homo sapiens (human)
Total number of polymer chains	2
Total formula weight	31573.34
Authors	Matsushima, M.,Song, H. (deposition date: 1994-09-14, release date: 1995-04-20, Last modification date: 2020-07-29)
Primary citation	Song, H.,Inaka, K.,Maenaka, K.,Matsushima, M. Structural changes of active site cleft and different saccharide binding modes in human lysozyme co-crystallized with hexa-N-acetyl-chitohexaose at pH 4.0. J.Mol.Biol., 244:522-540, 1994 Cited by PubMed: 7990138 DOI: 10.1006/jmbi.1994.1750 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.6 Å)

Structure validation