1LXG

Solution structure of alpha-cobratoxin complexed with a cognate peptide (structure ensemble)

1LXG の概要

• エントリーDOI: 10.2210/pdb1lxg/pdb
• 関連するPDBエントリー: 1lxh
• 分子名称: Long neurotoxin 1, Acetylcholine receptor protein, alpha chain (2 entities in total)
• 機能のキーワード: toxin, alpha-cobratoxin, nicotinic acetylcholine receptor, protein-protein interaction
• 由来する生物種: Torpedo californica (Pacific electric ray); 詳細
• 細胞内の位置: Secreted: P01391; Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein: P02710
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 10266.83

構造登録者

Zeng, H.,Hawrot, E. (登録日: 2002-06-05, 公開日: 2002-11-20, 最終更新日: 2022-02-23)

• 主引用文献: Zeng, H.,Hawrot, E.; NMR-based Binding Screen and Structural Analysis of the Complex Formed between alpha-Cobratoxin and an 18-mer Cognate Peptide Derived from the alpha1 Subunit of the Nicotinic Acetylcholine Receptor from Torpedo californica; J.Biol.Chem., 277:37439-37445, 2002; PubMed: 12133834; DOI: 10.1074/jbc.M205483200

実験手法

SOLUTION NMR