1LUV

CATALYTIC AND STRUCTURAL EFFECTS OF AMINO-ACID SUBSTITUTION AT HIS 30 IN HUMAN MANGANESE SUPEROXIDE DISMUTASE: INSERTION OF VAL CGAMMA INTO THE SUBSTRATE ACCESS CHANNEL

Summary for 1LUV

Entry DOI	10.2210/pdb1luv/pdb
Related	1ABM 1LUS 1LUW
Descriptor	Superoxide dismutase [Mn], MANGANESE (II) ION (3 entities in total)
Functional Keywords	human manganese superoxide dismutase, wild type, high resolution, mnsod, mn, oxidoreductase
Biological source	Homo sapiens (human)
Cellular location	Mitochondrion matrix: P04179
Total number of polymer chains	2
Total formula weight	44576.10
Authors	Hearn, A.S.,Stroupe, M.E.,Ramilo, C.A.,Luba, J.P.,Cabelli, D.E.,Tainer, J.A.,Silverman, D.N. (deposition date: 2002-05-23, release date: 2002-06-19, Last modification date: 2024-04-03)
Primary citation	Hearn, A.S.,Stroupe, M.E.,Cabelli, D.E.,Ramilo, C.A.,Luba, J.P.,Tainer, J.A.,Nick, H.S.,Silverman, D.N. Catalytic and structural effects of amino acid substitution at histidine 30 in human manganese superoxide dismutase: insertion of valine C gamma into the substrate access channel Biochemistry, 42:2781-2789, 2003 Cited by PubMed: 12627943 DOI: 10.1021/bi0266481 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.85 Å)

Structure validation