1LCY
Crystal Structure of the Mitochondrial Serine Protease HtrA2
Summary for 1LCY
Entry DOI | 10.2210/pdb1lcy/pdb |
Descriptor | HtrA2 serine protease (2 entities in total) |
Functional Keywords | apoptosis, serine protease, pdz domain, caspase activation, iap-binding, hydrolase |
Biological source | Homo sapiens (human) |
Cellular location | Mitochondrion intermembrane space: O43464 |
Total number of polymer chains | 1 |
Total formula weight | 35001.82 |
Authors | Li, W.,Srinivasula, S.M.,Chai, J.,Li, P.,Wu, J.W.,Zhang, Z.,Alnemri, E.S.,Shi, Y. (deposition date: 2002-04-07, release date: 2002-05-22, Last modification date: 2024-02-14) |
Primary citation | Li, W.,Srinivasula, S.M.,Chai, J.,Li, P.,Wu, J.W.,Zhang, Z.,Alnemri, E.S.,Shi, Y. Structural insights into the pro-apoptotic function of mitochondrial serine protease HtrA2/Omi. Nat.Struct.Biol., 9:436-441, 2002 Cited by PubMed: 11967569DOI: 10.1038/nsb795 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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