1LBL

Crystal structure of indole-3-glycerol phosphate synthase (IGPS) in complex with 1-(o-carboxyphenylamino)-1-deoxyribulose 5'-phosphate (CdRP)

1LBL の概要

• エントリーDOI: 10.2210/pdb1lbl/pdb
• 関連するPDBエントリー: 1IGS 1a53 1lbf
• 分子名称: indole-3-glycerol phosphate synthase, 1-(O-CARBOXY-PHENYLAMINO)-1-DEOXY-D-RIBULOSE-5-PHOSPHATE (3 entities in total)
• 機能のキーワード: beta barrel, tryptophan biosynthesis, protein ligand complex, substrate complex, lyase
• 由来する生物種: Sulfolobus solfataricus
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 28846.15

構造登録者

Hennig, M.,Darimont, B.D.,Kirschner, K.,Jansonius, J.N. (登録日: 2002-04-04, 公開日: 2002-09-18, 最終更新日: 2023-08-16)

• 主引用文献: Hennig, M.,Darimont, B.D.,Jansonius, J.N.,Kirschner, K.; The catalytic mechanism of indole-3-glycerol phosphate synthase: Crystal structures of complexes of the enzyme from Sulfolobus solfataricus with the substrate analogue, substrate, and product; J.Mol.Biol., 319:757-766, 2002; PubMed: 12054868; DOI: 10.1016/S0022-2836(02)00378-9

実験手法

X-RAY DIFFRACTION (2.4 Å)