1L7I

Crystal Structure of the anti-ErbB2 Fab2C4

Summary for 1L7I

• Entry DOI: 10.2210/pdb1l7i/pdb
• Descriptor: chimera of Fab2C4: "humanized" murine monoclonal antibody, SULFATE ION, ... (4 entities in total)
• Functional Keywords: ig domain, fab fragment, immune system
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 2
• Total formula weight: 47414.76

Authors

Vajdos, F.F.,Adams, C.W.,Breece, T.N.,Presta, L.G.,de Vos, A.M.,Sidhu, S.S. (deposition date: 2002-03-15, release date: 2002-07-10, Last modification date: 2011-07-13)

• Primary citation: Vajdos, F.F.,Adams, C.W.,Breece, T.N.,Presta, L.G.,de Vos, A.M.,Sidhu, S.S.; Comprehensive functional maps of the antigen-binding site of an anti-ErbB2 antibody obtained with shotgun scanning mutagenesis.; J.Mol.Biol., 320:415-428, 2002; PubMed: 12079396; DOI: 10.1016/S0022-2836(02)00264-4

Experimental method

X-RAY DIFFRACTION (1.8 Å)