1L1H

Crystal Structure of the Quadruplex DNA-Drug Complex

Summary for 1L1H

• Entry DOI: 10.2210/pdb1l1h/pdb
• Descriptor: 5'-D(*GP*GP*GP*GP*TP*TP*TP*TP*GP*GP*GP*G)-3', 3-PYRROLIDIN-1-YL-N-[6-(3-PYRROLIDIN-1-YL-PROPIONYLAMINO)-ACRIDIN-3-YL]-PROPIONAMIDE, POTASSIUM ION, ... (4 entities in total)
• Functional Keywords: g-quadruplex, oxytricha, four-stranded dna, dna
• Total number of polymer chains: 2
• Total formula weight: 8226.90

Authors

Haider, S.M.,Parkinson, G.N.,Neidle, S. (deposition date: 2002-02-16, release date: 2003-02-11, Last modification date: 2023-08-16)

• Primary citation: Haider, S.M.,Parkinson, G.N.,Neidle, S.; Structure of a G-quadruplex-Ligand Complex; J.Mol.Biol., 326:117-125, 2003; PubMed: 12547195; DOI: 10.1016/S0022-2836(02)01354-2

Experimental method

X-RAY DIFFRACTION (1.75 Å)