1KVH

NCSi-gb-bulge-DNA complex induced formation of a DNA bulge structure by a molecular wedge ligand-post-activated neocarzinostatin chromophore

1KVH の概要

• エントリーDOI: 10.2210/pdb1kvh/pdb
• 分子名称: 5'-D(*CP*CP*CP*GP*AP*TP*GP*C)-3', 5'-D(*GP*CP*AP*AP*TP*TP*CP*GP*GP*G)-3', SPIRO[[7-METHOXY-5-METHYL-1,2-DIHYDRO-NAPHTHALENE]-3,1'-[5-HYDROXY-9-[2-METHYLAMINO-2,6-DIDEOXYGALACTOPYRANOSYL-OXY]-5-(2-OXO-[1,3]DIOXOLAN-4-YL)-3A,5,9,9A-TETRAHYDRO-3H-1-OXA-CYCLOPENTA[A]-S-INDACEN-2-ONE]] (3 entities in total)
• 機能のキーワード: dna
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 6135.27

構造登録者

Gao, X.,Stassinopoulos, A.,Ji, J.,Kwon, Y.,Bare, S.,Goldberg, I.H. (登録日: 2002-01-26, 公開日: 2002-06-19, 最終更新日: 2022-02-23)

• 主引用文献: Gao, X.,Stassinopoulos, A.,Ji, J.,Kwon, Y.,Bare, S.,Goldberg, I.H.; Induced formation of a DNA bulge structure by a molecular wedge ligand-postactivated neocarzinostatin chromophore.; Biochemistry, 41:5131-5143, 2002; PubMed: 11955061; DOI: 10.1021/bi012112o

実験手法

SOLUTION NMR