1KSB

Relationship of Solution and Protein-Bound Structures of DNA Duplexes with the Major Intrastrand Cross-Link Lesions Formed on Cisplatin Binding to DNA

Summary for 1KSB

• Entry DOI: 10.2210/pdb1ksb/pdb
• Related: 1A84 1CKT
• Descriptor: 5'-D(*CP*TP*CP*CP*GP*GP*CP*CP*T)-3', 5'-D(*AP*GP*GP*CP*CP*GP*GP*AP*G)-3', Cisplatin (3 entities in total)
• Functional Keywords: deoxyribonucleic acid, cisplatin, dna, duplex, 9-mer, intrastrand cross-link, model j
• Total number of polymer chains: 2
• Total formula weight: 5773.64

Authors

Marzilli, L.G.,Saad, J.S.,Kuklenyik, Z.,Keating, K.A.,Xu, Y. (deposition date: 2002-01-11, release date: 2002-01-17, Last modification date: 2024-05-01)

• Primary citation: Marzilli, L.G.,Saad, J.S.,Kuklenyik, Z.,Keating, K.A.,Xu, Y.; Relationship of solution and protein-bound structures of DNA duplexes with the major intrastrand cross-link lesions formed on cisplatin binding to DNA.; J.Am.Chem.Soc., 123:2764-2770, 2001; PubMed: 11456962; DOI: 10.1021/ja0007915

Experimental method

SOLUTION NMR