1KSB

Relationship of Solution and Protein-Bound Structures of DNA Duplexes with the Major Intrastrand Cross-Link Lesions Formed on Cisplatin Binding to DNA

1KSB の概要

• エントリーDOI: 10.2210/pdb1ksb/pdb
• 関連するPDBエントリー: 1A84 1CKT
• 分子名称: 5'-D(*CP*TP*CP*CP*GP*GP*CP*CP*T)-3', 5'-D(*AP*GP*GP*CP*CP*GP*GP*AP*G)-3', Cisplatin (3 entities in total)
• 機能のキーワード: deoxyribonucleic acid, cisplatin, dna, duplex, 9-mer, intrastrand cross-link, model j
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 5773.64

構造登録者

Marzilli, L.G.,Saad, J.S.,Kuklenyik, Z.,Keating, K.A.,Xu, Y. (登録日: 2002-01-11, 公開日: 2002-01-17, 最終更新日: 2024-05-01)

• 主引用文献: Marzilli, L.G.,Saad, J.S.,Kuklenyik, Z.,Keating, K.A.,Xu, Y.; Relationship of solution and protein-bound structures of DNA duplexes with the major intrastrand cross-link lesions formed on cisplatin binding to DNA.; J.Am.Chem.Soc., 123:2764-2770, 2001; PubMed: 11456962; DOI: 10.1021/ja0007915

実験手法

SOLUTION NMR