1KQJ

Crystal Structure of a Mutant of MutY Catalytic Domain

1KQJ の概要

• エントリーDOI: 10.2210/pdb1kqj/pdb
• 関連するPDBエントリー: 1MUD 1MUN 1MUY
• 分子名称: A/G-SPECIFIC ADENINE GLYCOSYLASE, SULFATE ION, IRON/SULFUR CLUSTER, ... (5 entities in total)
• 機能のキーワード: all alpha-helix, two lobes, n-terminus contains helix-hinge-helix (hhh) and c-terminal domain contains iron sulfur cluster, hydrolase
• 由来する生物種: Escherichia coli
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 25807.98

構造登録者

Messick, T.E.,Chmiel, N.H.,Golinelli, M.P.,David, S.S.,Joshua-Tor, L. (登録日: 2002-01-06, 公開日: 2002-04-10, 最終更新日: 2023-08-16)

• 主引用文献: Messick, T.E.,Chmiel, N.H.,Golinelli, M.P.,Langer, M.R.,Joshua-Tor, L.,David, S.S.; Noncysteinyl coordination to the [4Fe-4S]2+ cluster of the DNA repair adenine glycosylase MutY introduced via site-directed mutagenesis. Structural characterization of an unusual histidinyl-coordinated cluster.; Biochemistry, 41:3931-3942, 2002; PubMed: 11900536; DOI: 10.1021/bi012035x

実験手法

X-RAY DIFFRACTION (1.7 Å)