1KI8

CRYSTAL STRUCTURE OF THYMIDINE KINASE FROM HERPES SIMPLEX VIRUS TYPE I COMPLEXED WITH 5-BROMOVINYLDEOXYURIDINE

1KI8 の概要

• エントリーDOI: 10.2210/pdb1ki8/pdb
• 分子名称: THYMIDINE KINASE, SULFATE ION, 5-BROMOVINYLDEOXYURIDINE, ... (4 entities in total)
• 機能のキーワード: phosphotransferase, thymidine kinase, viridae, ds-dna enveloped viruses, herpesviridae, alphaherpesvirinae, substrate analog, 5-bromovinyldeoxyuridine
• 由来する生物種: Herpes simplex virus (type 1 / strain 17)
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 72416.57

構造登録者

Champness, J.N.,Bennett, M.S.,Wien, F.,Visse, R.,Summers, W.C.,Sanderson, M.R. (登録日: 1998-05-15, 公開日: 1998-12-02, 最終更新日: 2024-02-14)

• 主引用文献: Champness, J.N.,Bennett, M.S.,Wien, F.,Visse, R.,Summers, W.C.,Herdewijn, P.,de Clerq, E.,Ostrowski, T.,Jarvest, R.L.,Sanderson, M.R.; Exploring the active site of herpes simplex virus type-1 thymidine kinase by X-ray crystallography of complexes with aciclovir and other ligands.; Proteins, 32:350-361, 1998; PubMed: 9715911; DOI: 10.1002/(SICI)1097-0134(19980815)32:3<350::AID-PROT10>3.0.CO;2-8

実験手法

X-RAY DIFFRACTION (2.2 Å)